Trajectory of flowing blood cells
in beating embryonic zebrafish heart Read More


Multidimensional Imaging
of Biological Processes The system tracked how firing neurons are connected to the movements of roundworms. The illustration shows the heart muscles of fish embryos in action. Read More
Flexible Bioelectonics Intravascular
Wirelessly Powered
Micropacers Read More
Flexible Bioelectonics Intravascular Deployment of Wirelessly
Powered Micro-Pacer The next generation of pacer by Parinaz Abiri Read More
Electrical Impedance Tomography Measuring Liver Fat Content
in Non-Alcoholic Fatty Liver Disease Multi-electrode array (MEA) is circumferentially positioned for EIT measurements of liver conductivity. Read More
Multi-channel for cardiac progenitor cells Multi-Dimensional
and Multi-Scale Imaging Superior axial resolution and contrast Architecture and Function Read More
Impaired autophagic flux Mechanotransduction
of Vascular Injury and Repair Mitochondrial homeostasis Temporal and spatial variations in shear stress Disturbed flow
Pulsatile flow Read More
Super-Resolution of Neuromuscular Junction Real-time light-sheet imaging Transgenic Tg (islet:gfp;mlcr:dsred) line gfp: motor neuron; dsred: somite/muscle Read More
4-D light sheat imaging and contractile function Shear Stress Modulation
of Trabeculation Gata1a morpholino and EPO mRNA micro-injection Notch 1b signaling and Nrg-1 mRNA rescue Read More
Flexible micro-electrodes IVUS-Guided Intravascular
Electrochemical Impedance Spectroscopy (EIS) Balloon stretchable EIS sensor Mechanically and metabolically unstable plaque Shear stress sensors Read More

Hsiai Lab UCLA Cardiovascular Engineering ResearchPrimarily on hemodynamics and mechanobiology

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SARS-CoV-2

Rapid Liposome Mimicking SARS-CoV-2 to Elucidate Thrombosis in Endothelialized Microfluidic Chip Read More

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    Vascular Mechanotransduction

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    Injured and Regenerating Myocardium

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    Cardiac Light-Sheet Imaging

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    Mechanically Unstable Plaque

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    Team Science Diversity&Equity

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The central theme of Dr. Hsiai's research program is primarily on hemodynamics and mechanobiology via the application of engineering principles and techniques, including Bio-MEMS and nanotechnology to study oxidative stress and to link physical and chemical properties with vascular biology.

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Lab News

  • 03/2021 UCLA Researchers Use AI to Show Multidimensional Imaging of Biological Processes Read More
  • 01/2021 Zhaoqiang Wang published his first author paper on Laser Light-field Imaging for cardiac morphogenesis by deep learning in Nature Methods.
  • 08/2020 Tzung Hsiai is elected to BMES Fellowship.
  • 07/2020 NIH T32 Research Service Awards for training biomedical scientists and engineers. Read More
  • 05/2020 Our team science is humbled by AHA's selection for COVID-19 rapid response from >750 applications! Read More
  • 04/2020 Congratulations on Dr. Yichen Ding's tenure track faculty positions in Biomedical Engineering!
  • 11/2019 Congratulations to Parinaz Abiri on being awarded the "The Edward K. Rice Outstanding Doctoral Student Award" from the School of Engineering & Applied Science!
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Recent Projects

Recent News

  • 04/2020 Congratulations to Varun Gadapati (MSIII)on being awarded the Dean's Leadership in Health and Science Scholarship!
  • 01/2020 In collaboration with School of Education, College Life Science, School of Engineering, and School of Medicine, Hsiai Lab coordinated and organized STEM outreach program on January 17, 2020.
  • 11/2019 Hsiai Lab will be co-chairing 2021 Gordon Research Conferences on "Biomechanics of Vascular Biology and Disease"
  • 11/2019 Congratulations on acceptance for publication in Nature Biotechnology with Professor Wei Gao (Caltech) and Professor Zhaoping Li (UCLA Human Nutrition) : A laser-engraved wearable sensor for sensitive detection of uric acid and tyrosine in sweat.
  • 09/2019 Congratulations to Dr. Rene Packard for being awarded the VA MERIT Award as an independent investigator!
  • 09/2019 Congratulations to Dr. Yichen Ding for being awarded the NIH K99/R00 transition to independence!
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